AppCleaner
Delete not only the app, but also all those pesky files that are associated with it.
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Also try: AppTrap
AppFresh
Stay up to date from one place with all your applications (third-party and Apple), widgets, preference panes and application plugins.
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AppMenuBoy
Easy access to all your apps (and only apps — none of the associated files) from the dock.
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Caffeine
Set your Mac to stay awake when it’s inconvenient to have it fall asleep, for example if you’re watching a movie.
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Carbon Copy Cloner
Carbon Copy Cloner not only creates a backup of your hard drive, but it’s also bootable.
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ClamXav
Virus? What’s that? It’s only a matter of time before OS X is hit by a truly virulent virus, and ClamXav should be able to help you detect it.
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CLIX
If you get the jitters when using Terminal, then CLIX may be for you. It has all those bizarre Unix commands built in, so all you have to do is find the right one and click it. And you just might learn a few along the way.
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Coconut Battery
Keep track of all the details of what’s happening with the battery in your portable mac as it happens.
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CornerClick
Take hot corners to the next level with the ability to open files, hide applications, open URLs, run AppleScripts and do the usual exposé actions.
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DasBoot
Turn your iPod into a recovery and diagnostic tool.
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Document Palette
Create new documents directly in open folders. With a folder active in Finder, press Control+Option+Command+N to make the palette appear, then select the document type you wish to create.
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EasyFind
Find folders,files and contents without the hassle of indexing. EasyFind is sort of like Spotlight for those who haven’t upgraded to Tiger.
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FastScripts Lite
Get instant access to your scripts by keyboard shortcut or menubar. Go beyond the AppleScript menu with many usability improvements and a refined interface.
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File List
Rename your files in batches, and maybe compile a playlist while you’re at it.
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FreeDMG
Quickly create disk images using drag and drop.
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Grand Perspective
Scan your folders to get a colourful view of what is inside them. Then hover with your cursor to see what files are represented. It’s a great way to see what’s taking up all the space. Disk Inventory X does much the same thing.
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Also try: Disk Inventory X
HotBox
Preference Pane allows you to sweep any portion of your screen and have it blow up to fill the screen. Both fun and practical.
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iBackup
Yet another backup app getting good reviews is called, in the tradition of the many iApps, iBackup. It gets especially high marks in the ease-of-use department.
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iStat menus
Keep tabs on what’s going on under the hood with stats in the menu bar for CPU, memory, disks, monitor, temperature, fans and power, and Bluetooth. Plus, customize the date and time to your heart’s content.
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Also try: MenuMeters
iTerm
Imagine Terminal with a slick interface, including tabs, and you’ve got iTerm.
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Lab Tick
Gain control over the backlit light on your PowerBook or MacBook Pro.
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Mac HelpMate
A good all-round utility that cleans, maintains and helps with troubleshooting.
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MacJanitor
There’s maintenance stuff your Unix-based computer does every night, but if you’re like me and turn it off at night, that won’t happen. So get MacJanitor to do it instead, and keep that Mac purring.
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MacTracker
A database of information on every Mac ever made — even those made by companies other than Apple. No detail is too obscure. You can even play startup chimes.
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MainMenu
Maintain, clean and optimize your mac — all from a handy icon in your menu bar.
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MemoryStick
See if you are running low on RAM with a display of your Mac’s memory allocation.
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MenuMeters
Keep track of what’s going on in your Mac with MenuMeters — a set of of monitors for CPU system load, disk activity, memory and network throughput. The cool thing is that they all sit on your menu bar.
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Monolingual
Claim valuable space on your hard drive by eliminating localization files for languages you never use.
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muCommander
A lightweight, cross-platform file manager featuring a Norton Commander style interface and running on any operating system with Java support.
Name Mangler
Rename and augment files in various ways, such as adding a prefix/suffix, changing case and numbering sequentially. Files and folders can be sorted in various ways, including path, created/modified date, comment, size and kind.
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Onyx
Onyx does a ton of stuff to help clean up and maintain your Mac. There are some things I can’t get to work, so I hesitate to give it a full recommendation. The program is quite popular, though, so you might have better luck. Another highly recommended troubleshooter is AppleJack.
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Also try: AppleJack
Preferential Treatment
Check your preference files for corruption, then give ‘em the treatment if you so desire.
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PsyncX
PsyncX allows you to make a backup of either one part of your hard drive or the entire hard drive to another computer. In addition, it allows users to schedule backups.
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RCDefault
Preference pane allows you to set default applications for the Internet, URLs, extensions, MIME types and file types.
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Reggy
Quickly visualize what a given regular expression will match given a test string. Also points out errors in your regular expression.
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rooSwitch Lite
Create profiles within the programs of your choice and switch between them.
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Scheduler
Schedule the automatic launching of applications, Applescript applets, documents, websites and file downloads at startup time or at a given time and date. There are many other scheduling options.
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Semulov
List all mounted volumes in your menubar, categorized by type. Clicking on a volume menu will unmount/eject that volume. Supports Growl unmount and mount notifications.
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Service Scrubber
If you’re overwhelmed by the number of services you find in your service menu, use this handy utility to scrub out the ones you don’t want. With services at a manageable level, you might actually use them.
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SilverKeeper
I use SilverKeeper for backup, and find it intuitive and easy. Actually I should use it more often, but that’s another story.
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SMARTReporter
Warns you of some ATA hard disk failures before they happen by periodically polling the S.M.A.R.T.-status of your hard disk.
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SuperDuper
If you’re confused about which backup utility to use, it’s understandable — there are many to choose from, and each is good in its own way. Recently, though, SuperDuper has risen head and shoulders above the others as the best of the best. The freeware version allows you backup and clone your drive. For extra features, you have to pay.
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Tags
Sort your files with tagged categories of your own making. Just duplicate the mother tag, drag files onto it and they will all share that category. Open the tag to find files that belong to it. Works great in Tiger. Your mileage may vary with Panther.
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Teleport
Enables multiple Macs to share a single keyboard and mouse over a network. TidBITS review
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The Unarchiver
Decompress several different compression formats, including some of the obscure ones the OS X can’t handle.
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TinkerTool
Not satisfied with the system preferences Apple gives you access to on your mac? TinkerTool lets you get at that hidden stuff too numerous to mention. If you’re the type who can’t leave well enough alone, then tinker away.
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Uno
Apply Tiger’s slick unified-toolbar interface to all our programs.
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UnRarX
Expand .rar archives and restore corrupted or missing archives using par2.
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Volumizer
Get volumes or disks to show up, more conveniently, in the dock or the menu bar instead of on the desktop.
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WhatSize
Get a hierarchical display by size of files and folders on the drive of your choice.
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Witch
Switch between open windows without reaching for your mouse. Click on a shortcut key, and up pops a neatly organized translucent list of windows to choose from.