Backup files and folders online with strong AES-256 encryption. Save space with incremental backups and data deduplication. Run backups on any machine through the web-based interface or via command line interface. Duplicati has a built-in scheduler and auto-updater.
Sync folders and volumes, or create a bootable clone of your Mac startup disk.
Customize backup intervals for Time Machine — by number of hours, by calendar date and time, or when inactive. Macworld has a good writeup.